The cultivation of tilapia, Oreochromis niloticus, is gradually expanding in the Pakistani region of Punjab. Working with tilapia presents management issues due to their early development and frequent spawning. Male tilapia develops more quickly than females, making them ideal for cultivation. Sex reversal is the most popular method among many that have been created to produce male tilapia for cultivation. Tilapia fry that has just hatched lack developed gonads. The development of the gonadal system can be controlled at this early stage of life history to create monosex populations. 17-methyltestosterone (MT), a synthetic androgen, is frequently used to reverse sex in Niletilapia in order to produce only male offspring (Oreochromis niloticus). Sex reversal is the term used to describe this phenomenon. Male and female development is guided by androgens and estrogens, respectively. The androgen most frequently used to control tilapia sex is methyltestosterone. Different treatment duration and dosage rate regimens have been examined. All rely on hormone therapy with sexually unequal fry. Partial or full harvests of spawning containers can yield fry. Earthen ponds, indoor and outdoor tanks, and cages with fine mesh nets are all employed for tilapia spawning (hapas). When fish are given the right amount of androgen from the start to the finish of the gonadal differentiation period, the resulting fish population will be heavily skewed toward males. The range of the fish output is 4400–7000 kg/ha. This production fluctuation might be the result of how the farmers manage their input and fish farms. The demand for tilapia is very strong here. The size of the fish affects how much fresh, iced seafood costs. Fish weighing 600–700 grammes this year sold for a decent price ($2.0/kg). However, the cost of fish was roughly half as much last year as it is this year. Southern and central Punjab are experiencing rapid growth in tilapia production. The challenges of expensive fish feed, low fry survival, fish health problems, fish processing, and fish marketing have nevertheless been brought up by fish farmers. The Punjab province of Pakistan’s tilapia culture is addressed in terms of its various facets.